Mutation

The mutation is an alteration in the structure or number of genes or chromosomes of a living organism that is transmitted to descendants by inheritance and produce a change its characteristic.

The most common mutation is the chromosome mutation that are changes in the total number of chromosomes, the duplication or deletion of genes or segments of a chromosome and rearrangement of genetic material within or between chromosomes.

One of the most frequent chromosomic mutation is Down Syndrome (95% of the cases)

The Down Syndrome is a duplication in the cromosome 21 and this cause problems with the way body and brain develop.